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PDF) Platelet-Derived S1P and Its Relevance for the Communication with Immune Cells in Multiple Human Diseases
TMPRSS2 structure-phylogeny repositions Avoralstat for SARS-CoV-2 prophylaxis in mice | bioRxiv
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Frontiers | Thymocytes in Lyve1-CRE/S1pr1f/f Mice Accumulate in the Thymus due to Cell-Intrinsic Loss of Sphingosine-1-Phosphate Receptor Expression
Plasma S1P (Sphingosine-1-Phosphate) Links to Hypertension and Biomarkers of Inflammation and Cardiovascular Disease: Findings From a Translational Investigation | Hypertension
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IJMS | Free Full-Text | Dissecting the Therapeutic Mechanisms of Sphingosine-1-Phosphate Receptor Agonism during Ischaemia and Reperfusion
Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis ...
PDF) Sphingosine-1-Phosphate as Lung and Cardiac Vasculature Protecting Agent in SARS-CoV-2 Infection
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Antioxidants | Free Full-Text | Sphingosine-1-Phosphate Alleviates Irradiation Induced Salivary Gland Hypofunction through Preserving Endothelial Cells and Resident Macrophages
U-shaped association between plasma sphingosine-1-phosphate levels and mortality in patients with chronic systolic heart failure: a prospective cohort study | Lipids in Health and Disease | Full Text
NLRP3 inflammasome priming and activation in cholestatic liver injury via the sphingosine 1-phosphate/S1P receptor 2/Gα(12/13)/MAPK signaling pathway | SpringerLink
IJMS | Free Full-Text | Sphingosine-1-Phosphate Receptor 3 Induces Endothelial Barrier Loss via ADAM10-Mediated Vascular Endothelial-Cadherin Cleavage
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IJMS | Free Full-Text | SARS-CoV-2 Infection: A Role for S1P/S1P Receptor Signaling in the Nervous System?
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Predictors for insufficient SARS-CoV-2 vaccination response upon treatment in multiple sclerosis - eBioMedicine
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Frontiers | Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System
Glycolytic enzyme PFKFB3 regulates sphingosine 1-phosphate receptor 1 in proangiogenic glomerular endothelial cells under diabetic condition | American Journal of Physiology-Cell Physiology
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S1P/S1PR3 axis promotes aerobic glycolysis by YAP/c-MYC/PGAM1 axis in osteosarcoma - eBioMedicine
Immunosuppressive and Anti-angiogenic Sphingosine 1-Phosphate Receptor-1 Agonists Induce Ubiquitinylation and Proteasomal Degradation of the Receptor - ScienceDirect
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Sphingosine‐1‐phosphate (S1P) induces potent anti‐inflammatory effects in vitro and in vivo by S1P receptor 4‐mediated suppression of 5‐lipoxygenase activity - Fettel - 2019 - The FASEB Journal - Wiley Online Library
Apolipoprotein M mediates sphingosine-1-phosphate efflux from erythrocytes | Scientific Reports
Sphingosine 1-Phosphate (S1P) Receptor Subtypes S1P1 and S1P3, Respectively, Regulate Lymphocyte Recirculation and Heart Rate - ScienceDirect
Sphingosine‐1‐phosphate (S1P) induces potent anti‐inflammatory effects in vitro and in vivo by S1P receptor 4‐mediated suppression of 5‐lipoxygenase activity - Fettel - 2019 - The FASEB Journal - Wiley Online Library
Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors | Nature Chemical Biology
Siponimod ameliorates metabolic oligodendrocyte injury via the sphingosine-1 phosphate receptor 5 | PNAS
PDF) Sphingosine-1-Phosphate Signaling in Cardiovascular Diseases
IJMS | Free Full-Text | A Sphingosine 1-Phosphate Gradient Is Linked to the Cerebral Recruitment of T Helper and Regulatory T Helper Cells during Acute Ischemic Stroke
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Frontiers | Fingolimod Alters Tissue Distribution and Cytokine Production of Human and Murine Innate Lymphoid Cells
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Sphingosine‐1‐phosphate receptor 1 signalling in T cells: trafficking and beyond - Garris - 2014 - Immunology - Wiley Online Library
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IJMS | Free Full-Text | In Vitro Characterization of Sphingosine 1-Phosphate Receptor 1 (S1P1) Expression and Mediated Migration of Primary Human T and B Cells in the Context of Cenerimod, a Novel,
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Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis | Scientific Reports
IJMS | Free Full-Text | The Ying and Yang of Sphingosine-1-Phosphate Signalling within the Bone